Bioinformatic pipeline

Outline

• Integrate pharmacogenomic variant calling in the hospital bioinformatic workflow using Nextflow
• Packaging the pharmacogenomic variant callers in a Singularity container for increased portability (the Pharmacotyper)
  • Using Aldy for genotyping of genes for absorption, distribution, metabolism, and excretion (ADME).
  • Using xHLA for genotyping of the HLA-gene.
• Making test for continuous integration of pharmacogenomic variant calling in the pipeline
  • Verified test data sets for Aldy are publicly available