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Unknown function

64 bytes removed, 11:05, 13 July 2018
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==Alleles with unknown biochemical consequence==
There are at least three kind of alleles that have unknown biochemical function
*Known PGx alleles that are classified with unknown functional ''Unknown function'' status by PharmGKB
*Alleles with variants that cause changes to the protein, but which are not classified by PharmGKB
*Alleles with variants that do not cause changes to the protein, and which are not classified by PharmGKB
  In the CPIC guidelines, some PGx alleles have unknown biochemical functional status. The dosing recommendation for such patients with ''Unknown functional status'' is to follow the normal medication advice. There are PGx-alleles This means that are classified *If the patient has an allele with biochemical unknown function, and otherwisethe recommended action is to follow normal dosing regime, all patients without a known PGx-even if the other allele match also have unknown has ''No function''.
==Alleles with normal bio-chemical consequence==
The bio-chemical function varies for all patients, and [[Normal function]] just means that the functional status is sufficiently close to the mean that the normal medication recommendation can be used.
There are at least two kind of alleles that have normal
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