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→Using Desktop Protégé for curation of PGx recommendations
==Using Desktop Protégé for curation of PGx recommendations==
Collaborative curation of PGx recommendations can quite easily be performed in WebProtégé, as explained above (of course, as with any tool, curators have to get used to it).
[[File:Protege compare guideline structure.png|thumb|By running the reasoner in the Desktop Protégé, we can ensure that the OUS guidelines and the CPIC guidelines are sematnically equivalent]]
When changing the semantic structure of the guidelines, as explained for Phenotype in the section above, we need to be sure that our new guideline structure is equivalent to the structure we get from PharmGKB.
Consistency can be checked automatically in the Desktop Protege by running a reasoner (e.g. keyboard shortcut Ctrl-r). We then see if our structurally different OUS guidelines give the same recommendations as the CPIC guidelines:[[File:Protege compare guideline structure.png|frameless|By running the reasoner in the Desktop Protégé, we can ensure that the OUS guidelines and the CPIC guidelines are sematnically equivalent]]
