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→How to define PGx alleles for next generation sequencing
==How to define PGx alleles for next generation sequencing==
As we saw in the previous section, PGx alleles are defined as collections of one or more SNPs, INDELs or structural variants. When a patient is sequenced by next generation sequencing ([[NGS]]) technology we may typically observe more variants than those which are included in any individual PGx allele definitions.
[[File:Variant tree outline.png|thumb|The 16 possible haplotypes for a four loci, decomposed variant calling]]
This means that